Immunohistochemical study on the insulin-, glucagon-, somatostatin-, and pancreatic polypeptide secreting cells in Korean native goat

Lee, Heungshik S.; Lee, In-se; Kang, Tae-cheon; Kim, Jin-sang; Yi, Seong-joon

Korean Journal of Veterinary Research 1995;35(1):45-54.

Heungshik S. Lee¹, In-se Lee¹, Tae-cheon Kang¹, Jin-sang Kim², Seong-joon Yi³

¹College of Veterinary Medicine, Seoul National University
²College of Rehabilitation Science, Taegu University
³College of Veterinary Medicine, Kyungpook National University

한국재래산양 췌장의 insulin, glucagon, somatostatin 및 pancreatic polypeptide 분비세포에 관한 면역조직화학적 연구

이흥식¹, 이인세¹, 강태천¹, 김진상², 이성준³

¹서울대학교 수의과대학
²대구대학교 재활과학대학
³경북대학교 수의과대학

Abstract

Pancreatic endocrine cells containing glucagon, insulin, somatostatin and pancreatic polypeptide were identified in the pancreas of the Korean native goat by using immunohistochemical method. Glucagon immunoreative cells were oval or fusiform in shape and located at the periphery of the pancreatic islets. Insulin immunoreactive cells were round or oval in shape and occupied throughout the pancreatic islets except the small area of the periphery. Somatostatin immunoreative cells were oval and elliptical, and mainly located at the periphery of the pancreatic islets. Some of these cells had a cytoplasmic process. Pancreatic polypeptide immunoreactive cells were elliptical or polyhedral and located at the periphery of the pancratic islets where two or more cells formed a cell cluster. The distribution rates of glucagon, insulin, somatostatin and pancreatic polypeptide immunoreactive cells were 24.4%, 44.3%, 13.2% and 18.1% respectively.

Key Words: Korean native goat pancreas, glucagon cell, insulin cell, somatostatin cell, pancreatic polypeptide cell