Effect of relative humidity in swine house on pathogenesis of swine pleuropneumonia |
Hyun-kyu Jeong1, Jeong-hee Han1, Jae-hoon Kim2 |
1Department of Veterinary Medicine, Kangwon National University 2Veterinary Research Institute |
돈사의 상대습도가 돼지흉막폐렴의 병인에 미치는 영향 |
정현규1, 한정희1, 김재훈2 |
1강원대학교 수의학과 2수의과학연구소 |
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Abstract |
The effect of relative humidity in swine house on swin pleuropneumonia was examined in piglets experimentally infected with Actinobacillus pleuropneumoniae serotype 5. A total of 20 piglet were grown under 30~40%, 41~50%, 51~64% and 65~80% relative humidity chambers after intratracheal inoculation of A pleuropneumoniae. Characteristic fibrinous pleuropneumonia was observed in the pigs grown at the low relative humidity groups. The detailed results were as follows : 1. Growth performance and environment conditions were lower than high relative humidity groups. 2. Characteristic histopathological findings were fibrinous pleuritis and pneumonia accompanied congestion, hemorrhage, thrombosis and edematous change. 3. Antigenic distribution of inoculated bacterium was found mainly in alveolar macrophages or accumulated foci of macrophages adjacent to necrotic area. 4. Characteristic electron microscopic findings were proliferation of type II pneumocyte with increased lamella bodies and activated alveolar macrophages with pseudopods and widening of interstitium. |
Key Words:
relative humidity, Actinobacillus pleuropneumonia, fibrinous pleuropneumonia, alveolar macrophage, type II pneumocyte |
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