| A comparison of single dose efficacy of Mycoplasma hyopneumoniae bacterin in swine farms with different serological patterns of PRRSV and PCV2 |
|
Hye Kwon Kim1, Hyoung Joon Moon1, Eun Mi Kim1, Jeong Sun Yang1, Seong Jun Pakr1, Yuzi Luo1, Chul Seung Lee2, Dae Sub Song2, Bo Kyu Kang2, Jaebum Lee3, Bong Kyun Park1 |
1College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University
2Research Unit, Green Cross Veterinary Products
3Hankuk Academy of Foreign Studies |
|
|
| Abstract |
|
This study was to evaluate the efficacy of single dose Mycoplasma hyopneumoniae (M. hyo)-vaccination in the swine farms which had different serological patterns of porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2). A minimum of 240 pigs from each farm was applied, allocating M. hyo vaccinated and control groups. The PRRSV and PCV2 infections were analyzed by serological method (commercial ELISA kit). After administrating pigs a single dose of M. hyo vaccine or control saline at 3 weeks of age, serum antibodies to M. hyo, PRRSV and PCV2 were monitored at 4, 10, 16 and 22 weeks of age. Mortality, weight changes, feed conversion ratio (FCR) and lung score were also evaluated. A single-dose vaccination of M. hyo bacterin was efficacious to reduce mycoplasmal lung lesions and induce good humoral immune response. However, FCR was improved only in one of the three farms where showed seronegative status to both PRRSV and PCV2 in the period from 4 to 16 weeks of age. These results might imply that M. hyo vaccine alone could not overcome the PRRSV and PCV2 infection-associated wasting in the field condition. Therefore, the control of PRRSV and PCV2 should be considered to obtain the better effects of M. hyo vaccination. |
| Key Words:
Efficacy, Mycoplasma hyopneumoniae, PCV2, PRRSV, Vaccine |
|
PDF Links
Full text via DOI
Download Citation
