Korean Journal of Veterinary Research 2008;48(3):323-326.
Granulosa cell tumor in a sow
Hyeong-Seok Kim1, Sang-Chul Kang2, Ji-YouI Jung1, Hyun-Sup Kim3, Dae-Yong Kim4, Jae-Hoon Kim1
1College of Veterinary Medicine, Cheju National University
2Preclinical Research Center Chemon Inc
3Happy Farm
4College of Veterinary Medicine, Seoul National University
돼지의 과립막세포 종양
김형석1, 강상철2, 정지열1, 김현섭3, 김대용4, 김재훈1
1제주대학교 수의과대학
2켐온 전임상 연구센터
3행복한 농장
4서울대학교 수의과대학
Abstract
A two-year-old mixed breed sow was requested to the Veterinary Pathology Laboratory of Cheju National University with a clinical signs of severe abdominal pain and sudden death. Grossly, there was severe hemorrhage in abdominal cavity. Most of internal parenchymas and subcutaneous muscle showed severe pale discoloration. Both ovaries were enlarged with oval to round protruding multilobular masses and dark red in color. And they were firm and contained multiple small cysts in their cut surface. Histopathologically, numerous neoplastic granulosa cells had spherical-to-oval, hyperchromatic nuclei and scant eosinophilic cytoplasms were distributed with follicular pattern in ovarian masses. And the typical Call-Exner bodies, distinctive microcavityies, were observed in the center of small neoplastic follicles. Based on the gross and histopathologic findings, this case was diagnosed as granulosa cell tumor. In our best knowledge, this is believed to be the first report of granulosa cell tumor in a sow in Korea.
Key Words: Call-Exner bodies, granulosa cell tumor, ovary, sow


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