Caseous lymphadenitis by Corynebacterium pseudotuberculosis in a Saanen dairy goat (Capra hircus aegagrus)

Shin, Dong-Ho; Song, Yun-Kyung; Byun, Jae-Won; Kim, Ha-Young; Kim, Hyoung-Soon; Woo, Gye-Hyeong; Lee, O-Soo; Jung, Byeong Yeal

Korean Journal of Veterinary Research 2010;50(1):25-28.

Dong-Ho Shin, Yun-Kyung Song, Jae-Won Byun, Ha-Young Kim, Hyoung-Soon Kim, Gye-Hyeong Woo, O-Soo Lee, Byeong Yeal Jung

National Veterinary Research and Quarantine Service

Corynebacterium pseudotuberculosis에 의한 유산양의 가성결핵 증례

신동호, 송윤경, 변재원, 김하영, 김형순, 우계형, 이오수, 정병일

국립수의과학검역원 질병진단센터

Abstract

Caseous lymphadenitis (CLA) is a chronic and contagious disease of sheep and goats caused by Corynebacterium (C.) pseudotuberculosis. A four-year-old female Saanen dairy goat was submitted to the Animal Disease Diagnostic Center at National Veterinary Research and Quarantine Service. The clinical signs of the goat were emaciation, abortion and quadriplegia. The multifocal nodules of lymph nodes were encapsulated and filled with whitish caseous contents on the cut surface. Histopathologically, lymph nodes displayed suppurative and necrotizing granulomas. Caseous necrosis was diffusely observed in the center of the lymph nodes. Gram positive bacilli were shown in the lesions. C. pseudotuberculosis was isolated and confirmed by the biochemical tests and PCR assay. Based on clinical signs, histopathological examination and bacterial isolation, we diagnosed this case as CLA. To our knowledge, this is the first report of CLA in a Saanen dairy goat in Korea.

Key Words: caseous lymphadenitis, Corynebacterium pseudotuberculosis, goat