| Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016-2017 |
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Kiju Kim1, Jong-Young Choi1, Kwang-Soo Lyoo2, Tae-Wook Hahn1 |
1College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University
2Korea Zoonosis Research Institute, Chonbuk National University |
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| Abstract |
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The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016-2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3-100% homology at the nucleotide (deduced amino acid 86.3-100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea. |
| Key Words:
capsid proteins, genetic variation, phylogenetic analysis, porcine circovirus type 2 |
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