Histopathological Observations of the Natural Case and Experimental Occurence of Perirenal Edema in Pig

Cho, Sung-whan; Lee, Cha-soo

Korean Journal of Veterinary Research 1984;24(2):173-181.

¹Department of Histology, Chungnam National University College of Medicine
²Department of Veterinary Medicine, College of Agriculture, Gyeongbug National University

돼지의 Perirenal Edema의 자연발생예(自然發生例)와 실험적발생예(實驗的發生例)의 병리학적소견(病理學的所見)

조성환¹, 이차수²

¹충남대학교 농과대학 조직학교실
²경북대학교 농과대학 수의학과

Abstract

This paper dealt with the histopathological observations of the perirenal edema in pigs and rabbits administered with Amaranthus retroflexus, based on the clinical and pathological observations of the porcine perirenal edema naturally occurred in Korea. The results observed are summarized as follows; In the natural case, clinical signs were trembling, weakness and incoordination of the hindquarters, followed by sternal recumbency, coma and death. Death usually occurred within 24 hours after the signs of illness appeared. In gross findings, the grayish yellow fluid in the perirenal area was observed in each case. In some cases, the amount of fluid in the thoracic and abdominal cavities was increased and the yellowish red color of the hydrothorax and ascites was seen. When the renal capsule was incised, the kidneys were enlarged and congested and petechiae on the cortical surface and blood clots on the capsule appeared. In microscopical findings, there were cloudy swelling, hyaline droplets and necrosis of the convoluted tubules containing proteinaceous casts and a few oxalate crystals. In addition, interstitial and perivascular edema, distention of the Bowman's space and the convluted tubules and hemorrhages were recognized. In the weanling pigs and the adult pig fed various weeds, including Amaranthus retroflexus, Euxolus blitum and Portulaca oleracea, the pigs fed Amaranthus retroflexus appeared clinical signs and pathological findings of perirenal edema usually seen in the pigs of natural cases. In the pigs fed Euxolus blitum or fed Portulaca oleracea, neither clinical signs nor pathological changes were seen. It was regarded that this disease was affected with Amaranthus retroflexus, but there was no sensitivity in the adult pigs.