| Oral malodor-reducing effects by oral feeding of Weissella cibaria CMU in Beagle dogs |
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Kyung-Hyo Do1, Ho-Eun Park1, Mi-Sun Kang2, Jong-Tae Kim2, Ji-Eun Yeu2, Wan-Kyu Lee1 |
1College of Veterinary Medicine, Chungbuk National University
2Research Institute, Oradentics Inc. |
| Weissella cibaria CMU 경구투여가 비글의 구취 저하에 미치는 효과 |
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도경효1, 박호은1, 강미선2, 김종태2, 여지은2, 이완규1 |
1충북대학교 수의과대학
2(주)오라덴틱스 구강연구소 |
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| Abstract |
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This study assessed the effects of Weissella cibaria (W. cibaria) CMU on oral health in male and female beagles (n = 18) by measuring oral malodor and periodontal disease-related parameters (calculus, plaque, and gingivitis indices). Oral malodor and indicators of periodontal disease were assessed in five treatment groups: negative control (scaling and 0.24 mg of maltodextrin, n = 3), positive control (0.24 mg of maltodextrin, n = 3), and W. cibaria CMU groups (each n = 4) at low (CMU-L, $2{ imes}10^7$ colony forming unit [CFU]), medium (CMU-M, $2{ imes}10^8CFU$), and high (CMU-H, $2{ imes}10^9CFU$) concentrations. After feeding with W. cibaria CMU for 6 weeks, total volatile sulfur compound concentrations in the CMU-L ($2.0{pm}1.04ng/10mL$), CMU-M ($2.4{pm}1.05ng/10mL$), and CMU-H ($2.6{pm}1.33ng/10mL$) groups were significantly lower than in the positive control group ($3.2{pm}1.65ng/10mL$). Also, CMU-L ($1.4{pm}0.83ng/10mL$) and CMU-H ($1.9{pm}1.14ng/10mL$) groups had methyl mercaptan levels lower than that in the positive control group ($2.4{pm}1.21ng/10mL$) at week 2. The plaque index was significantly lower in the CMU-H group ($4.5{pm}0.28$) than in the positive control group ($5.9{pm}1.08$) at week 6. W. cibaria CMU could be useful as a novel oral hygiene probiotics for reducing volatile sulfur compounds production and inhibiting plaque growth in companion animals. |
| Key Words:
Beagle, Weissella cibaria CMU, methyl mercaptan, oral malodor, plaque index |
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