Studies on the internal decontamination of radioiodine

Chung, In-yong; Kim, Tae-hwan; Chung, Hyun-woo; Chin, Soo-yil; Yun, Taik-koo

Korean Journal of Veterinary Research 1988;28(2):391-396.

In-yong Chung, Tae-hwan Kim, Hyun-woo Chung, Soo-yil Chin, Taik-koo Yun

Laboratory of Radiation Hazard Korea Cancer Center Hospital, Korea Advanced Energy Research Institute

Radioiodine의 체내오염(體內汚染)에 대(對)한 긴급처치연구(緊急處置硏究)

정인용, 김태환, 정현우, 진수일, 윤택구

원자력병원 방사선인체장해연구실, 한국에너지연구소

Abstract

Appreciable radiation exposures certainly occur in the workers who handle radioiodine in biochemical research, nuclear medicine diagnostics with the development of nuclear industries. But in the case of occurring the nuclear accidents, the early medical treatment of radiation injury should be necessary but little was reported in korea till now. Accordingly, to achieve of the basic data for protective roles and medical treatment of radiation injury, the present studies were carried out to evaluate the decontamination of radioiodine by the administration of the antithyroid drugs. The results observed are summarized as follows: 1. The administration of sodium iodide and potassium iodide results in rapid excretion of radioiodine and reduction of the whole body retention than the saline-only group. 2. Reguarding to thyroid protective effects, sodium iodide, potassium iodide and saline were effected significant in order. 3. In the control(saline) group, if administered with enough fluids, the whole body retention of radioiodine is reduced temporary shifts. But as far as radioprotective effects is concerned, saline was not more in the protective effects than the other groups. In conclusion, in case of nuclear accidents, if being administered sodium iodide and saline as quickly as possible, the radioprotective effects against the radiation hazard might be markedly increased in the internal contamination of radioiodine.

Key Words: radioiodine decontamination