Korean Journal of Veterinary Research 1991;31(3):303-309.
Virological studies on the puppies experimentally infected with canine parvovirus isolated in Korea
Hae-yeon Choi1, Moo-hyung Jun2, Seong-kuk Park2
1Northern Branch of Chungbuk Animal Health Laboratory
2College of Veterinary Medicine, Chungnam National University
환견으로 부터 분리한 canine parvovirus의 실험적 감염 자견에 대한 바이러스학적 연구
최해연1, 전무형2, 박성국2
1충북가축위생시험소 북부지소
2충남대학교 수의과대학
To investigate the pathogenicity and virological properties of TJ-89-2 strain of canine parvovirus(CPV -2) that was isolated from the diseased puppies in Korea, seven puppies-were inoculated intraorally with the isolate at the HA titer of 8,192. All of the puppies showed the signs of anorexia, vomiting, diarrhea and died at the 5th to 10th days post inoculation (pi). All of the fecal samples from the puppies revealed significantly high HA titers afterward the 5th days pi. Body temperature and the number of total leucocytes were slightly increased at the early stage of infection, but extremly decreased at the stage of collapse. HI titers of the sera began to increase at the 3rd to 4th days pi, reaching 512 to 1,024 at the 4th to 5th days pi.
Key Words: Experimentally infected puppies, canine parvovirus, Korean isolates

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