Ultrastructure of virus particles in the liver of piglets infected with porcine enterovirus serotype 3 |
Tae-kyun Shin1, Cha-soo Lee2, Min-do Huh3 |
1Department of Veterinary Medicine, Cheju National University 2College of Veterinary Medicine, Kyungpook National University 3Department of Fish Pathology, National Fisheries University of Pusun |
Enterovirus 감염 돼지의 간에서 virus의 형태학적 관찰 |
신태균1, 이차수2, 허민도3 |
1제주대학교 수의학과 2경북대학교 수의과대학 3부산수산대학교 어병학과 |
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Abstract |
Oral infection of colostrum-deprived, neonatal piglets with porcine enterovirus serotype 3 can result in hepatic lesions with a short incubation period. In the thin section of the affected liver, crystalline arrays of virus particles characteristic of picornavirus were identified in the sinusoid endothelial cells and Kupffer cells. There were also cytoplasmic aggregates of electron- dense, virus-like particles in the hepatocytes. These findings suggest that porcine enterovirus serotype 3 has hepatotropism as well as neurotropism. |
Key Words:
porcine enterovirus, liver, picornavirus, ultrastructure |
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