Electron microscopic study on the insulin-, glucagon-, somatostatin-, and pancreatic polypeptide secreting cells in Korean native goat

Lee, Heungshik S.; Lee, In-se; Kang, Tae-cheon; Won, Moo-ho; Yi, Seong-joon

Korean Journal of Veterinary Research 1995;35(1):55-65.

Heungshik S. Lee¹, In-se Lee¹, Tae-cheon Kang¹, Moo-ho Won², Seong-joon Yi³

¹College of Veterinary Medicine, Seoul National University
²College of Medicine, Hallym University
³College of Veterinary Medicine, Kyungpook National University

한국재래산양 췌장의 insulin, glucagon, somatostatin 및 pancreatic polypeptide 분비세포에 관한 전자현미경적 연구

이흥식¹, 이인세¹, 강태천¹, 원무호², 이성준³

¹서울대학교 수의과대학 해부학교실
²한림대학교 의과대학 해부학교실
³경북대학교 수의과대학 해부학교실

Abstract

Ultrastructures of pancreatic endocrine cells containing glucagon, insulin, somatosratin and pancreatic polypeptide were studied in the pancreas of the Korean native goat by immunohistochemical and elecron microscopy. Glucagon immunoreatctive cells were round or fusiform in shape and contained secretory granules of 200-260 nm in diameter. The secretory granules were high in electron density and had a halo between the limiting membrane and the central granule core. Insulin immunoreactive cells were round or oval in shape, and contained various sizes of secretory granules from 135 to 300 nm in diameter. The secretory granules were low or moderate electron density and had a variform halo. Somatostatin immunoreactive cells were elliptical or fusiform shape with cytoplasmic processes. They contained the secretory granules of 140-320 nm with moderate electron densities. Pancreatic polypeptide immunoreactive cells were elliptical or fusiform and contained small secretory granules with high electron densities. The secretory granules were 120-230 nm in diameter and the least in number.

Key Words: Korean native goat pancreas, glucagon cell, insulin cell, somatostatin cell, pancreatic polypeptide cell