| Haptoglobin as an early indicator of infection in pigs |
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Jin-san Moon1, Hyang-mi Nam1, Bok-gyeong Ku1, Yi-seok Joo1, Suk-chan Jung1, Jong-yeom Kim1, Yong-ho Park2 |
1National Veterinary Research Institute, RDA
2College of Veterinary Medicine, Seoul National University |
| 돼지에서 감염의 조기진단 지표로서의 Haptoglobin 적용에 관한 연구 |
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문진산1, 남향미1, 구복경1, 주이석1, 정석찬1, 김종염1, 박용호2 |
1농촌진흥청 수의과학연구소
2서울대학교 수의과대학 |
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| Abstract |
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Sera of pigs with clinically normal and infectious conditions were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE) to demonstrate the specific changes in protein profile. In the sera from pigs with infection, haptoglobin with a 40KDa protein was found to be increased as compared to that of sera from normal pigs. As a rapid detection method for monitoring infections at large-scale farms, one of acute phase protein, haptoglobin, was selected to compare the concentrations between infectious and non-infectious conditions. Haptoglobin concentrations were low in pigs with clinically normal conditions but significantly increased in pigs with Aujesky's disease, hog cholera and parvo-virus infection. The studies provide that haptoglobin can be used as an indicator to monitor infections early at farm level. |
| Key Words:
pig, acute phase protein, haptoglobin |
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