A study on efficacy of chitosan on bovine mastitis

Moon, Jin-san; Joo, Yi-seok; Ku, Bok-gyeong; Kim, Jong-yeom; Kim, Duck-won; Park, Yong-ho; Hahn, Tae-wook

Korean Journal of Veterinary Research 1998;38(1):71-76.

Jin-san Moon¹, Yi-seok Joo¹, Bok-gyeong Ku¹, Jong-yeom Kim¹, Duck-won Kim², Yong-ho Park³, Tae-wook Hahn⁴

¹National Veterinary Research Institute, RDA
²Samyang Pharma-Chemical Co., LTD.
³Seoul National University
⁴University of Georgia

젖소 유방염에 대한 키토산의 효능에 관한 연구

문진산¹, 주이석¹, 구복경¹, 김종염¹, 김덕원², 박용호³, 한태욱⁴

¹수의과학연구소
²삼양약화학
³서울대학교 수의과대학
⁴미국 조지아대학교

Abstract

The effects of chitosan on mastitis in lactating holstein cows were evaluated. Fifty six cows with intramammary infection(IMI) from nine farms were selected and the cows were fed with diets which contained 15~20g chitosan per day for 5~7 days. The milk samples were obtained from cows at 7 days and 14 days after administration to determine effect of the curing of mastitis and the reduction of somatic cell counts(SCC). The average value of SCC levels in quarter milk from the cows administrated with chitosan significantly decreased up to 31.8% and 47.7% at 7 and 14 days, respectively(P<0.05). The cure rates of chitosan for Stapylococcus aureus, coagulase-negative Staphylococci, Streptococci spp, other gram positive bacteria and coliforms were 30.4, 42.8, 33.3, 66.6 and 54.5 % respectively. Twenty three out of 64 cases were cured by feeding with chitosan. The results showed that administration of chitosan could reduce SCC in milk and improve cure rates of bovine mastitis caused by microorganisms. The further studies will be pursued to study on the mechanism of chitosan in the immune responses of cows with mastitis.

Key Words: chitosan, cows, mastitis, somatic cell count