Korean Journal of Veterinary Research 1998;38(1):71-76.
A study on efficacy of chitosan on bovine mastitis
Jin-san Moon1, Yi-seok Joo1, Bok-gyeong Ku1, Jong-yeom Kim1, Duck-won Kim2, Yong-ho Park3, Tae-wook Hahn4
1National Veterinary Research Institute, RDA
2Samyang Pharma-Chemical Co., LTD.
3Seoul National University
4University of Georgia
젖소 유방염에 대한 키토산의 효능에 관한 연구
문진산1, 주이석1, 구복경1, 김종염1, 김덕원2, 박용호3, 한태욱4
3서울대학교 수의과대학
4미국 조지아대학교
The effects of chitosan on mastitis in lactating holstein cows were evaluated. Fifty six cows with intramammary infection(IMI) from nine farms were selected and the cows were fed with diets which contained 15~20g chitosan per day for 5~7 days. The milk samples were obtained from cows at 7 days and 14 days after administration to determine effect of the curing of mastitis and the reduction of somatic cell counts(SCC). The average value of SCC levels in quarter milk from the cows administrated with chitosan significantly decreased up to 31.8% and 47.7% at 7 and 14 days, respectively(P<0.05). The cure rates of chitosan for Stapylococcus aureus, coagulase-negative Staphylococci, Streptococci spp, other gram positive bacteria and coliforms were 30.4, 42.8, 33.3, 66.6 and 54.5 % respectively. Twenty three out of 64 cases were cured by feeding with chitosan. The results showed that administration of chitosan could reduce SCC in milk and improve cure rates of bovine mastitis caused by microorganisms. The further studies will be pursued to study on the mechanism of chitosan in the immune responses of cows with mastitis.
Key Words: chitosan, cows, mastitis, somatic cell count

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