Morphogenetical characteristics of Korean wild rat (Rattus norvegicus) |
Je-Kyung Seong1, Young-min Yun1, Ji-young Park1, Seung-hyun Oh1, Seon-gil Do2, Hee-kyung Jin2, Byung-hwa Hyun3, Jun-gyo Suh2, Yang-seok Oh2 |
1Department of Laboratory Animal Medicine, Medical Research Center, Yonsei University College of Medicine 2Experimental Animal Center, College of Medicine, Hallym University 3Bioresource Program, KRIBB, KIST |
한국 야생 랫드의 형태 유전학적 특성 |
성제경1, 윤영민1, 박지영1, 오승현1, 도선길2, 진희경2, 현병화3, 서준교2, 오양석2 |
1연세대학교 의과대학 임상의학연구센터 실험동물부 2한림대학교 의과대학 실험동물부 3생명공학연구소 유전자원센터 |
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Abstract |
The morphometrical characteristics such as external measurements and mandible size assessment in mice and rats have to be highly heritable and sufficiently variable between strains in order to calculate a strain specific profiles. The coat color of Korean wild rats were observed and morphometric analysis of external measurements were carried out on Korean wild rats compared to laboratory strains in order to clarify the genetic characteristics of Korean wild rats and to establish background data as a domestication of Korean wild rats for new laboratory strain. Korean wild rats were captured from Chunchon and Hoengsong. 4 inbred and 1 outbred strains of rats were used in this study for the comparison of genetic characteristic of Korean wild rats. Total body length, head length, tail length, hind foot length and ear length were measured and then statistical analysis were carried out by discrimiant analysis. The coat color of Korean wild rat showed golden white in ventral portion and dark agouti in dorsal portion. Korean wild rats could be distinguished from the other laboratory strains distinctly by morphogenetical analysis. There was significant variations among Korean wild rat compared to those of the other laboratory strains of rat. This study may provide that Korean wild rats have a unique genetic characterization compared to those of other inbred strains of rats based on morphogenetical characteristics by external measurements. |
Key Words:
morphogenetics, Korean wild rat, Rattus norvegicus, discriminant analysis |
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