Korean Journal of Veterinary Research 2000;40(2):345-360.
Effect of dietary chlortetracycline on productivity and respiratory disease in pigs
Young-bang Kwon1, Won-hyung Lee1, Wan-kyu Lee1, Jong-koo Kang1, Young-chul Jung2, Sung-hoon Kim3, Byung-woo Han3
1College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University
2Jung P&C Institute
3Cheil Breeding Stock Co., Ltd.
Chlortetracycline(CTC)의 사료 첨가가 돼지의 생산성과 호흡기 병변에 미치는 영향
권영방1, 이원형1, 이완규1, 강종구1, 정영철2, 김성훈3, 한병우3
1충북대학교 수의과대학 및 동물의학연구소
3제일종축 농장
The effects on CTC (T1) and CTC, Sulfathiazole and Penicillin Combination (T2) medication in feed through one life cycle of pigs, namely, weaning, mating, farrowing, lactation, growing, finishing and slaughter, were tested under local condition. In sow phase, productivity and the number of microflora in urine before and after medication of CTC were studied and average daily gain and feed conversion rate were checked during growing and finishing period. All pigs reached at 155 days old were slaughtered for pathological examination. 1. Litter size, farrowing rate and survival rate at birth were improved by CTC medication from weaning to 21th day after mating and mortality of piglet at weaning, 25 days after farrowing, was reduced in the CTC medication group, but no siginificant. 2. The number of microflora in the sow urine was changed with the medication at 200ppm of CTC in feed. In particular, the number of E coli, Samonella and Staphylococci were reduced by CTC medication. 3. The average daily gain and feed conversion rate of grower and finisher pigs was improved significantly in both treated groups, most in the high level CTC (T1) medicated group and was lowest in the control group. 4. The number of infected lungs was reduced not significant by both treatments (as % pneumonic lesions Co 66.7%, T1 47.1%, T2 31.4%) and the severity of lung lesions was significantly reduced by both high level of CTC and CTC combination medication in feed. 5. Although there were no statistical differences in atrophic rhinitis based on turbinate scores among the 3 groups, the number of mild and moderate (Grade 2 and 3) infections was higher in the control group (9/36) than in the treated groups (T1 2/34 & T2 4/35).
Key Words: Chlortetracycline, productivity, respiratory disease, medication program

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