Korean Journal of Veterinary Research 2000;40(4):671-675.
Structure of hemolymph node in rats
Cheol-beom Park1, Je-kyung Seong2, In-se Lee1, Heungshik S. Lee1, Joon-sup Lee1, Yeo-sung Yoon1
1College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University
2Department of Laboratory Animal Medicine, Medical Research Center, College of Medicine, Yonsei University
랫드의 혈림프절 구조
박철범1, 성제경2, 이인세1, 이흥식1, 이준섭1, 윤여성1
1서울대학교 수의과대학
2연세대학교 의과대학 임상의학연구센터 실험동물부
It has been known that the hemolymph node is one of the lymphoid organs found normally in ruminants and some rodents, and this organ shares morphological and functional characteristics of lymph node and spleen. To clarify the rigorous definition of morphological structures and functions of the hemolymph node in Sprague-Dawley(SD) rats, we examined these organs of SD rats gross anatomically and light microscopically. The hemolymph nodes were normally found in the abdominal cavity and in the neck of SD rats. This organ was surrounded by a thin connective tissue capsule and there was a hilus. The parenchyma comprised a cortex of lymphatic nodules and diffuse lymphatic tissues, and a medulla of diffuse lymphatic tissues arranged in cords. Afferent and efferent lymph vessels were observed but there was no extensive subcapsular and medullary sinuses. These sinuses were filled with erythrocytes. The stroma of hemolymph nodes was composed of reticular cells and fibers, and many lymphocytes, granulocytes, erythrocytes, plasma cells, macrophages and megakaryocytes were supported by the reticular network. The above findings suggest that the hemolymph nodes of SD rats may take part in blood formation, blood filtration and immune reaction.
Key Words: hemolymph node, SD rat, gross anatomy, histology

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