Korean Journal of Veterinary Research 2004;44(1):65-71.
Control of canine respiratory and diarrheal disease using egg yolk antibodies I. Induction of antibody in hens immunized with combined antigens of Bordetella bronchiseptica, parvovirus and canine distempervirus
Hee-soo Lee1, Jong-man Kim1, Seng-ryong Woo1, Byeong-yeal Jung1, Yun-Sang Cho1, Dong-seob Tark1, Sook-kyoung Lim1, Han sang Yoo2, Yong-dhuk Yoon3, Woo Huh4, Young-sik Mun4, Jin-sik Oh3
1National Veterinary Research and Quarantine Services
2College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University
3Green Cross Veterinary Science Institute
4Dae Sung Microbiology Laboratory
난황면역제를 이용한 개 주요 소화기 및 호흡기질병 방제에 관한 연구 I. 개 보데텔라, 파보바이러스 및 개디스템퍼 항원의 닭에서의 면역반응
이희수1, 김종만1, 우승룡1, 정병열1, 조윤상1, 탁동섭1, 임숙경1, 유한상2, 윤용덕3, 허원4, 문영식4, 오진식3
2서울대학교 수의과대학 및 농생명공학부
This study was carried out to produce IgY against B. bronchiseptica, parvovirus and distemper virus that are major pathogens in alimentary and/or respiratory diseases of dogs. In the comparison of adjuvants, ISA70 was the best in the rapid induction and maintence of antibody titers. Agglutination antibody titers against B. bronchiseptica were 1:1,280 ~ 1:10,240 in sera and 1:160 ~ 1:1,280 in egg yolk. Hemagglutination inhibition(HI) titers against parvovirus in sera and egg yolk were 1:80 ~ 1:320 and 1:64 ~ 1:256, respectively. Virus neutralization titers against canine distemper was 1:8 ~ 1:64 in sera and egg yolk. These results suggested that egg yolk antibody titers could be variable according to a sort of adjuvant and antigens of the pathogens.
Key Words: egg yolk antibodies, B. bronchiseptica, parvovirus, distemper virus, immune response

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