| Effects of teat dipping disinfectant containing biodegradable iodophor microspheres on preventing dry period intramammary infection in dairy cows |
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Cheol-Yong Hwang1, Jong-Min Kim1, Hwa-Young Youn1, Bo Han2, Hong-Ryul Han1 |
1College of Veterinary Medicine, Seoul National University
2College of Veterinary Medicine, China Agricultural University |
| 생분해성 iodophor microsphere 함유 유두침지 소독제의 건유기 젖소에서의 유방내 신규감염 예방 효과 |
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황철용1, 김종민1, 윤화영1, 한박2, 한홍율1 |
1서울대학교 수의과대학
2중국 농업대학교 동물의학원 |
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| Abstract |
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1% iodophor loaded microspheres of PLGA (Poly[DL-Lactide-co-Glycolide]) were prepared by solvent evaporation method and were applied to the cows on dry period for evaluating it's preventive effects on intramammary infections. The morphology of the microspheres were evaluated using scanning electron microscopy and their releasing patterns were investigated. On investigating idophor releasing patterns of the microsphere, burst releasing pattern was detected until 2 days after in vitro incubation and sustained releasing was observed until 4 weeks. In field trial of teat dipping solution containing idophor loaded microspheres in dry cows showed significant preventive effects of intramammary infection caused by S. aureus, S. agalactiae, coagulase negative Staphylococci and coliform bacteria (p<0.05). |
| Key Words:
microsphere, teat dipping solutin, iodophor, dairy cow |
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