Korean Journal of Veterinary Research 2004;44(2):311-315.
Magnetic resonance imaging characteristic of lymph nodes: Comparison of T1 and T2 weighted image in normal rabbits
Ki-chang Lee1, Min-cheol Choi1, Ho-Jung Choi1, Jung-hee Yoon1, Seong-hong Choi2, Woo-kyung Moon2, Jin-Wook Chung2
1College of Veterinary Medicine, Seoul National University
2College of Medicine, Seoul National University
림프절의 자기공명영상의 특징: 가토에서 T1과 T2 강조영상의 비교
이기창1, 최민철1, 최호정1, 윤정희1, 최승홍2, 문우경2, 정진욱2
1서울대학교 수의과대학
2서울대학교 의과대학
The detection of lymph node metastasis is an important step in tumor staging and is significant for therapy planning. It has been challenged to yield an appropriate image with diagnostic methods such as Magnetic Resonance (MR) and Computed Tomography (CT). Though CT has been used widely and accessed easily to show internal organs, it can hardly provide difference between lymph node and adjacent vessel or fat tissue. It has been well established that MR can reveal the subtle discrepancy within soft tissue. This study investigated the suitability of MR lymph node imaging without contrast enhancement by comparison of T1-weighted image (T1WI) and T2- weighted image (T2WI) in ten normal rabbits. According to the pulse sequence optimized from preliminary study, T1-weighted spin-echo (repetition time/echo time=400/12 ms) and T-2 weighted fast spin-echo (repetition time/echo time=3500/84 ms) images covering the hind limbs and pelvic region were acquired at 1.5 T. Two radiologists scrupulously evaluated the MR images in consensus. And signal intensity of lymph nodes was compared with that of adjacent fat. Statistical analysis showed that T1-weighted coronal image visualized the lymph nodes (iliac, superficial inguinal and popliteal lymph nodes) quickly and consistently rather than T2-weighted one. Conclusively, T1WI for evaluation of lymph nodes is moderately better than T2WI and appears to have potential for quick and sufficient mapping of the lymph nodes. In addition, this normal MR image of lymph nodes could be applied to further study for the evaluation of lymphatic system in abscess and tumor bearing animal model.
Key Words: T1-weighted image, T2-weighted image, lymph node, rabbit

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