Efficacy of Ciprofloxacin for the Control of Streptococcal Infection in Cultured Fish, Flounder(Paralichtyhs olivaceus) and Eel(Anguilla japonica)

Park, Se Chang; Heo, Gang-Joon

Korean Journal of Veterinary Research 2004;44(4):643-648.

Se Chang Park¹, Gang-Joon Heo²

¹Collage of veterinary medicine, Seoul National University
²Collage of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National university

넙치(Paralichthys olivaceus) 및 뱀장어(Anguilla japonica)의 연쇄구균즈에 대한 시프로플로삭신의 치료 효과

박세창¹, 허강준²

¹서울대학교 수의과대학
²충북대학교 수의과대학 및 동물의학연구소

Abstract

Efficacy of ciprofloxacin was evaluated in laboratory and field studies for control of streptococcal infection in flounder and eel. In disc diffussion test, all streptococcal strains showed high sensitivity to the ciprofloxacin. Minimum inhibitory concentrations of ciprofloxacin against all streptococcal strains used in this study were less than $0.195{mu}g/ml/$. In laboratory studies where fishes were challanged with Streptococcus iniae, significant reductions in mortality were observed among fish receiving ciprofloxacin (in fed) at 100 mg/kg/body weight or more daily for 3 d when compared with mortality of non-medicated controls. Similar results were achieved when 100 mg/kg/body weight of ciprofloxacin was used in field trials.

Key Words: ciprfloxacin, efficacy, streptococcal infection, cultured fish