| Comparison of sedative effects using intermittent intravenous bolus injection with tiletamine-zolazepam, xylazine-ketamine, and propofol in beagle dogs |
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Soo-Han Lee1, Chun-Sik Bae2, Byeong-han Lee1, Byung-Hyun Chung1 |
1College of Veterinary Medicine, Veterinary Science Research Institute, Konkuk University
2College of Veterinary Medicine, Biotechnology Research Institute, Chonnam National University |
| 비글견에서 tiletamine-zolazepam, xylazine-ketamine 및 propofol의 간헐적 일시 정맥주사에 의한 진정효과의 비교 |
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이수한1, 배춘식2, 이병한1, 정병현1 |
1건국대학교 수의과대학 및 수의과학연구소
2전남대학교 수의과대학 및 생물공학연구소 |
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| Abstract |
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To compare the sedative effects using intermittent intravenous bolus injection with tiletamine-zolazepam (n = 5, TZ group), xylazine-ketamine (n = 5, XK group) and propofol (n = 5, PI group), we investigated the changes of hemodynamic (heart rate, arterial pressure), $SpO_2$, rectal temperature, respiratory rate and pain score during 60 minute sedation and 40 minute recovery period in beagle dogs. The value of rectal temperature was significantly higher in PI groups (p<0.05) during recovery period. The value of heart rate was significantly lower in XK group (p<0.05) during sedation. The changes of respiratory rate were similar tendency in all groups. The change of $SpO_2$ was stable during sedation and value was significantly higher in PI group (p<0.05) during recovery period. The value of systolic arterial pressure (SAP) was significantly lower in XK group (p<0.05) than PI group during sedation and recovery period. Low analgesic effect occurred in PI group. We concluded that intravenous anesthesia by intermittent bolus injection with propofol is useful in stabilizing rectal temperature, $SpO_2$ and hemodynamic during sedation and provide fast recovery, but have low analgesic effect. |
| Key Words:
propofol, sedation, tiletamine-zolazepam, xylazine-ketamine, beagle dog |
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