A case of protein losing nephropathy in a dog infected with canine Babesia gibsoni

Kim, Ha-Jung; Park, Chul; Jung, Dong-In; Kang, Byeong-Teck; Kim, Ju-Won; Lim, Chae-Young; Park, Hee-Myung

Korean Journal of Veterinary Research 2006;46(1):77-81.

Ha-Jung Kim, Chul Park, Dong-In Jung, Byeong-Teck Kang, Ju-Won Kim, Chae-Young Lim, Hee-Myung Park

College of Veterinary Medicine, Konkuk University

Abstract

A 1-year and 6-month-old, intact male, Shih-tzu dog was referred to the Konkuk University Veterinary Teaching Hospital, due to ascite, melena, severe anemia, and polyuria/polydipsia. Complete blood count showed moderate leukocytosis, lymphocytosis, monocytosis, and microcytic hypochromic nonregenerative anemia. On serum biochemistry profiles, hypoalbuminemia and hypoproteinemia were observed, and proteinuria was detected on urinalysis. Pleural effusion and mild ascites were noted in radiological findings, and bilateral nephromegaly was noted on ultrasonography. Babesia gibsoni was detected by PCR. Babesiosis and glomerular disease was treated at a time with prednisolone and buparvaquone. This therapeutic regime was very efficacious and clinical sings were rapidly improved. Proteinuria and severe anemia were disappeared following therapy.

Key Words: babesiosis, glomerulonephritis, protein losing nephropathy, proteinuria