Apocrine sweat gland adenocarcinoma in a cat

Park, Min-Hyeok; Jung, Ji-Youl; Jo, Suk-Hee; Kim, Jae-Hoon; Lee, Jin-Yong; Lee, Mi-Kyung; Kim, Jae-Hoon

Korean Journal of Veterinary Research 2009;49(2):157-161.

Min-Hyeok Park¹, Ji-Youl Jung¹, Suk-Hee Jo¹, Jae-Hoon Kim¹, Jin-Yong Lee², Mi-Kyung Lee², Jae-Hoon Kim¹

¹College of Veterinary Medicine, Jeju National University
²Cats and Dogs Animal Clinic

고양이의 땀샘 선암종 증례

박민혁¹, 정지열¹, 조숙희¹, 김재훈¹, 이진용², 이미경², 김재훈¹

¹제주대학교 수의과대학
²캣츠 앤 독스 애니멀 크리닉

Abstract

A 11-year-old female mixed cat with subcutaneous mass around the left 5th mammary glands was presented to local animal hospital. According to history taking, the mass recurred 2 times on the same site of abdomen. After surgical excision, subcutaneous mass was referred to Pathology Department of Veterinary Medicine in the Jeju National University. Grossly, round to oval, milky yellow or pale red nodules, measuring 0.1${sim}$1 cm in diameter, were occupied in the subcutis. Microscopically, the most neoplastic sweat glands were proliferated in the dermis and subcutis. Most tubules were lined by round to oval shaped epithelium with eosinophilic cytoplasm, hyperchromatic nuclei with high mitotic figures and severe central necrosis. The neoplastic epithelium also had periodic acid-Schiff-positive diastase-resistant cytoplasmic granules, but was negative for Perl's iron stain. Based on the gross, histopathologic and special staining, this cat was diagnosed as apocrine sweat gland adenocarcinoma. In our best knowledge, this is the first report of apocrine sweat gland adenocarcinoma around abdominal mammary gland in a cat.

Key Words: apocrine sweat gland adenocarcinoma, cat, diastase-resistant, PAS stain, tumor