Korean Journal of Veterinary Research 2010;50(1):63-69.
Application of thromboxane synthetase inhibitor (Ozagrel HCl) in feline infectious peritonitis
Tae-Sin Kim, Sun-Hee Lee, Soo-Jung Lim, Hyung-Jin Park, Eun-Sik Song, Dae-Wook Jung, Duck-Hwan Kim, Kun-Ho Song
College of Veterinary Medicine, Chungnam National University
고양이 전염성 복막염에 thromboxane synthetase inhibitor (Ozagrel HCl)의 적용
김태신, 이선희, 임수정, 박형진, 송은식, 정대욱, 김덕환, 송근호
충남대학교 수의과대학
Abstract
A Persian chinchila (2 years old, intact female) and a Korean domestic shorthaired cat (3 months, intact male) were referred to the Veterinary Medical Teaching Hospital of Chungnam National University with tachypnea. The two cats were diagnosed as feline infectious peritonitis (FIP) by blood and blood chemical examination, radiographic examination, RT-PCR and electrophoresis analysis of pleural effusion. Thromboxane synthetase inhibitor (Ozagrel HCl, 5 mg/kg, twice a day) was administered to the Persian chinchila and Korean domestic shorthair for 13 days and 16 days, respectively. Pleural effusion disappeared after treatment with Ozagrel HCl. Further study is needed to establish a new application protocol of Ozagrel HCl for FIP cases.
Key Words: feline infectious peritonitis, Ozagrel HCl, pleural effusion, thromboxane synthetase inhibitor
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