Bovine respiratory syncytial virus infection in a Jeju native black calf

Kim, Hyun-Tae; Jung, Ji-Youl; Jo, Suk-Hee; Lee, Kyoung-Kap; Kim, Jae-Hoon; Kim, Jae-Hoon

Korean Journal of Veterinary Research 2010;50(2):139-143.

Hyun-Tae Kim, Ji-Youl Jung, Suk-Hee Jo, Kyoung-Kap Lee, Jae-Hoon Kim, Jae-Hoon Kim

College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University

제주흑우 송아지에서 소 합포체성 폐렴의 발생

김현태, 정지열, 조숙희, 이경갑, 김재훈, 김재훈

제주대학교 수의과대학 및 수의과학연구소

Abstract

A 2-month-old male Jeju native black calf with respiratory distress was died and requested to the Veterinary Pathology Laboratory of Jeju National University for diagnosis. Grossly, lungs were focally attached to the pleura and heart with fibrin. Purple red sublobar consolidations were distributed in both apical and cardiac lobes of lungs. Histopathologically, diffuse severe bronchointerstitial pneumonia characterized by multifocal necrotizing bronchiolitis, formation of numerous multinucleated syncytial cells in bronchiolar and alveolar lumens, and diffuse alveolar wall thickening were observed in lungs. Eosinophilic intracytoplasmic inclusions were observed in bronchiolar epithelial cells and syncytial cells. According to reverse transcriptase polymerase chain reaction (RT-PCR), bovine respiratory syncytial virus (BRSV) was detected in the lung of calf. Based on the histopathologic findings and RT-PCR, this calf was diagnosed as BRSV infection. In our best knowledge, this is the first case of BRSV infection in Jeju native black calf.

Key Words: bovine respiratory syncytial virus, bronchointerstitial pneumonia, Jeju native black calf, lung