Korean J Vet Res > Volume 51(2); 2011 > Article
Korean Journal of Veterinary Research 2011;51(2):171-175.
DOI: https://doi.org/10.14405/kjvr.2011.51.2.171    Published online June 1, 2011.
Malignant Sertoli cell tumor in Shih Tzu dog
Sang-Chul Kang1, Hyoung-Seok Yang1, Ji-Youl Jung1, Eun-Hye Jung1, Hee-Chun Lee2, Eui-Kyung Hwang3, Jae-Hoon Kim1
1College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University
2College of Veterinary Medicine, Gyeongsang National University
3College of Life Science and Natural Resources, Sangji University
Abstract
Malignant Sertoli cell tumor was diagnosed in a 5-year-old male Shih Tzu dog. Clinical features of the dog were anorexia, urinary incontinence, constipation, anemia, alopecia, and epistaxis. The dog also had unilateral cryptorchid testis in the abdomen. Several abdominal and thoracic masses were identified on radiography. Grossly, the cryptorchid testicular mass was markedly enlarged to 8 cm in diameter. On cut surface, firm and well demarcated milk-white neoplastic areas were irregularly separated by white fibrous bands. Histologically, the testicular mass was diagnosed as tubular pattern Sertoli cell tumor. In addition, abdominal and mediastinal lymph nodes metastasis were found. Immunohistochemically, the tumor cells were strongly positive for vimentin and neuron specific enolase, but negative for S-100 and cytokeratin.
Key Words: cryptorchid testis, dog, immunohistochemistry, malignant Sertoli cell tumor


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