Korean J Vet Res > Volume 51(3); 2011 > Article
Korean Journal of Veterinary Research 2011;51(3):227-231.
DOI: https://doi.org/10.14405/kjvr.2011.51.3.227    Published online September 1, 2011.
Evaluation of the lateral ventricle using MRI in normal micropigs
Mihyun Choi, Namsoon Lee, Kangjae Yi, Junyoung Kim, Mincheol Choi
Department of Veterinary Medical Imaging and Research Institute for Veterinary Science, Seoul National University
This study was undertaken to assess the lateral ventricle, which was some portion of brain and related to congenital anomalies, from 1, 2, 4, and 8 months of age in healthy micropigs. They were induced general anesthesia and performed magnetic resonance imaging (MRI) with a 0.3 Tesla magnet. Each age group was evaluated by three subjects such as lateral ventricular volume, ventricular volume ratio and asymmetry. T1 weighted transverse images were acquired for calculation of lateral ventricular and corresponding brain parenchyma areas. The ratio of bilateral ventricle areas used to analyze the asymmetry. The mean ventricular volumes of each month were $676.74{pm}25.58mm^3$ (1 month-old), $630.64{pm}143.84mm^3$ (2 month-old), $992.12{pm}106.03mm^3$ (4 month-old) and $1172.62{pm}237.57mm^3$ (8 month-old), respectively. The ventricular volume ratio was the smallest at 2 month-old and re-increased from that age. The ratio was significantly different between 2 month-old and other age groups (p < 0.05). The value of bilateral area ratio showed within 1.5 in all experimental animals. Consequently the lateral ventricle showed a positive correlation with aging and symmetric shapes in both sides. The developmental pattern of the lateral ventricle provides basic data in micropigs as an experimental animal model for physiological and neurosurgical approach.
Key Words: brain, lateral ventricle, micropigs, MRI

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