Korean J Vet Res > Volume 53(2); 2013 > Article
Korean Journal of Veterinary Research 2013;53(2):83-88.
DOI: https://doi.org/10.14405/kjvr.2013.53.2.083    Published online June 25, 2013.
Field evaluation of Enterotoxigenic Escherichia coli-specific bacteriophage (ΦCJ19) as a feed additive
Anna Yoo1, Seung Bin Cha1, Min Kyoung Shin1, Hong Tae Park1, Hyo Sil Seo2, Jae Won Kim2, Han Sang Yoo1
1College of Veterinary Medicine, Seoul National University
2Research Institute of Biotechnology, CJ Cheil Jedang Co.
Enterotoxigenic Escherichia coli 특이 박테리오파지 (ΦCJ19)의 사료 첨가제로서의 사양 평가
유안나1, 차승빈1, 신민경1, 박홍태1, 서효실2, 김재원2, 유한상1
1서울대학교 수의과대학
2CJ 제일제당 바이오기술연구소
Field efficacy of enterotoxigenic Escherichia coli-specific phage (${Phi}CJ19$) as a feed additive was evaluated in weaning piglets. Fifty-four piglets at 3-4 weeks old were allocated in three different groups and two of them were fed with bacteriophage at different concentrations ($10^6PFU/kg$ feed and $10^8PFU/kg$ feed, respectively) for 30 days. Body weight and feed intake were measured at 10 days interval and body condition and fecal score were inspected every day. Based on the measurement, feed conversion rate (FCR) and average daily gain (ADG) of each group during 30 days were analyzed. The analysis suggests that the bacteriophage may help the improvement of FCR and ADG at $10^8PFU/kg$ of bacteriophage feeding group in 30 days. A result from analysis of fecal score indicates that the bacteriophage also may help to relieve the intermittent diarrhea in post-weaning stage. Those results suggest that bacteriophage might help the growth of piglets in post-weaning stage.
Key Words: bacteriophage, enterotoxigenic Escherichia coli, feed additive, field efficacy

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