Study on the antimicrobial activities of herbal extracts against Helicobacter pylori

Lee, Hyun-A; Kim, Okjin

doi:2013.53.2.117

Korean J Vet Res > Volume 53(2); 2013 > Article

Brief Communication

Korean Journal of Veterinary Research 2013;53(2):117-123.
DOI: https://doi.org/10.14405/kjvr.2013.53.2.117 Published online June 25, 2013.

Study on the antimicrobial activities of herbal extracts against Helicobacter pylori

Hyun-A Lee¹, Okjin Kim²

¹Korean Medicine-Based Herbal Drug Research Group, Korea Institute of Oriental Medicine
²Center for Animal Resources Development, Wonkwang University

Helicobacter pylori에 대한 항균활성을 가진 천연물의 검색과 항균력 비교 연구

이현아¹, 김옥진²

¹한국한의학연구원 한의신약연구그룹
²원광대학교 동물자원개발연구센터

Abstract

Infection with Helicobacter (H.) pylori is strongly associated with duodenal and gastric ulcers. Substantial epidemiological data has revealed that high rates of H. pylori infection might be related to high rates of gastric cancer. In this study, a medicinal herbal extracts were examined and screened for anti-H. pylori activity. Seventy percent ethanol was used for herbal extraction. For anti-H. pylori activity study, the inhibitory zone tests with 74 herbal compounds were conducted. As the results, thirteen compounds including Cinnamomi Cortex, Magnoliae Cortex and Meliae Fructus were revealed strong anti-H. pylori activities.

Key Words: antibacterial activity, anti-helicobacter, Helicobacter pylori, herb, in vitro