Metastatic thyroid C-cell carcinoma in a beagle dog |
So-Ra Lee1, Mi-Kyoung Lee1, Kyoung-A Youp1, Ah-Ra Lee1, Sung-Jun Won1, Myung-Chul Kim2, So-Yeon Kim2, Yongbaek Kim2 |
1Irion Animal Hospital 2The Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University |
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Abstract |
An adult beagle dog was presented with a cervical mass detected by palpation and computed tomography. Fine needle aspirates revealed numerous epithelial cells with plasmacytoid appearance and frequent naked nuclei. Histologically, the mass consists of multiple packets of neoplastic cells and extensive areas of necrosis and fibrosis. Neoplastic cells were also found in submandibular lymph nodes. Immunohistochemistry showed that neoplastic cells were positive for calcitonin and negative for thyroglobulin. Based on these findings, the cervical mass was diagnosed as thyroid C-cell carcinoma. Almost one year after the surgical excision, the dog remains healthy without any symptom of recurrence or metastasis. |
Key Words:
calcitonin, C-cell carcinoma, dog, metastasis, thyroid |
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