| Biological activities and acute oral toxicity of citronella and lemongrass oil |
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Ji-Yong Park1, Jin-Yoon Kim2, Seung-Hee Jang1, Hae-Jung Kim1, Seung-Jin Lee2, Seung-Chun Park2 |
1Cleanbio Research Institute
2College of Veterinary Medicine, Kyungpook National University |
| Citronella 및 lemongrass oil의 생리활성 및 단회 경구 투여 독성시험 |
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박지용1, 김진윤2, 장승희1, 김해중1, 이승진2, 박승춘2 |
1(주)크린바이오 부설연구소
2경북대학교 수의과대학 |
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| Abstract |
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This study was performed to investigate the antibacterial, antioxidant, and termite repellent effects of citronella oil (CiO) and lemongrass oil (LO). When the antibacterial activity against Staphylococcus (S.) aureus with various levels of antibacterial resistance were tested, a 0.05% concentration of CiO and LO completely inhibited the growth of all tested S. aureus strains. Evaluation of the antioxidant effect demonstrated that the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of CiO was 2~3 times greater than that of LO. Among trial products made with various combinations of CiO and LO, a CiO : LO ratio of 6 : 4 had the most potent termite repellent effects. Assessment of acute toxicity of the trial product showed that the $LD_{50}$ was more than 2,000 mg/kg. Based on the above results, CiO and LO have antibacterial, antioxidant, and termite repellent activities. Therefore, both compounds could be potential termites repellent reagents. |
| Key Words:
citronella oil, lemongrass oil, DPPH, termites repellent |
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