Genetic analysis of env and gag gene fragments of bovine leukemia virus identified in cattle from Korea

Kim, Yeon-Hee; Lee, Eun-Yong; Oem, Jae-Ku; Kim, Seong-Hee; Lee, Myoung-Heon; Lee, Kyoung-Ki; Park, Se-Chang

doi:2015.55.1.53

Korean J Vet Res > Volume 55(1); 2015 > Article

Brief Communication

Korean Journal of Veterinary Research 2015;55(1):53-56.
DOI: https://doi.org/10.14405/kjvr.2015.55.1.53 Published online March 24, 2015.

Genetic analysis of env and gag gene fragments of bovine leukemia virus identified in cattle from Korea

Yeon-Hee Kim¹, Eun-Yong Lee¹, Jae-Ku Oem¹, Seong-Hee Kim¹, Myoung-Heon Lee¹, Kyoung-Ki Lee¹, Se-Chang Park²

¹Division of Animal Diseases Diagnosis, Animal and Plant Quarantine Agency
²College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University

Abstract

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leukosis. This study was conducted to clarify the molecular characteristics of BLVs obtained from a specific region in Korea. Proviral BLVs were detected in anti-BLV antibody-positive blood samples by PCR. Env and gag fragments were sequenced and compared to previously published reference sequences. Analysis of the env gene sequence revealed that the YI strain was highly similar to genotype 1, including United States and Japanese strains. The gag gene sequence had the highest degree of similarity with a Japanese strain.

Key Words: bovine leukemia virus, cattle, env gene, gag gene