| Detection and characterization of avian hepatitis E virus from broiler breeders and layers in Korea |
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Hyun-Woo Moon, Haan Woo Sung, Hyuk Moo Kwon |
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Laboratory of Veterinary Microbiology, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University |
| 육용종계와 산란계에서 avian hepatitis E virus의 검출 및 특성 규명 |
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문현우, 성환우, 권혁무 |
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강원대학교 수의과대학.동물의학종합연구소 |
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| Abstract |
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The helicase genes and hypervariable regions (HVRs) of three avian hepatitis E viruses (HEVs) detected at three different farms were sequenced and characterized. Two isolates (DW-L and GI-B2) were classified as genotype 2 and one isolate (GR-B) was classified as genotype 1. A phylogenetic tree, based on the helicase gene and HVR nucleotide sequences, revealed the newly detected viruses and other avian HEVs were classified similarly. Unlike previously reported avian HEVs, the DW-L isolate detected in broiler breeders with characteristic lesions of avian HEV had no proline-rich motif in its HVR, suggesting that the proline-rich motif is non-essential for viral replication and infection. |
| Key Words:
avian hepatitis E virus, helicase gene, hypervariable region, sequences |
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