Korean J Vet Res > Volume 59(4); 2019 > Article
Korean Journal of Veterinary Research 2019;59(4):219-222.
DOI: https://doi.org/10.14405/kjvr.2019.59.4.219    Published online February 17, 2020.
Nailbed malignant melanoma in three dogs
Hyoung-Nam Jo1, Myeong-Won Suh1, Joo-Ok Lee2, Jae-Hoon Kim1
1College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University
2Ekklim Anima Hospital
Correspondence:  Jae-Hoon Kim, Tel: 82-64-754-3387, Fax: 82-64-702-9920, 
Email: kimjhoon@jejunu.ac.kr
Abstract
Three 8-12-year-old male cocker spaniels presented with an appendicular mass accompanied by pain, inflammation, lameness, and loss of nail in the digits of the forelimb or hindlimb. A histological examination revealed dermal masses of the digit composed of numerous neoplastic cells with marked pleomorphism and high mitosis. The neoplastic cells showed a strong invasive tendency into the epidermis and adjacent bony tissues, such as distal phalanx. Immunohistochemistry of the neoplastic cells in three masses revealed positive reactions for Melan-A. These three dogs were diagnosed as nailbed malignant melanoma in the digit based on the history, clinical signs, and histopathologic features.
Key Words: digit, distal phalanx, dog, Melan-A, nailbed malignant melanoma


About
Browse articles
For contributors
Policy
Editorial Office
#401-1, 85 Bldg., College of Veterinary Medicine, Seoul National University
1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea
Tel: +82-2-880-1229    Fax: +82-2-878-9762    E-mail: jvs@ksvs.or.kr                

Copyright © 2023 by The Korean Society of Veterinary Science.

Developed in M2PI

Close layer
prev next