The Effects of Propylthiouracil on the Metabolic Rate and the Thyroidal Activity in Korean Native Goats

Kwun, Jong Kuk; Sung, Jai Ki; Rhee, Young So; Lee, Yong-Bin; Chung, Yung Chai

Korean Journal of Veterinary Research 1967;7(2):31-34.

Jong Kuk Kwun¹, Jai Ki Sung¹, Young So Rhee¹, Yong-Bin Lee¹, Yung Chai Chung²

¹College of Agriculture, Seoul National University
²College of Agriculture, Choong Nam National University

Propylthiouracil이 재래산양(在來山羊)의 대사율(代謝率) 및 갑상선(甲狀腺) 기능(機能)에 미치는 영향

권종국¹, 성재기¹, 이영소¹, 이용빈¹, 정영채²

¹서울대학교 농과대학
²충남대학교 농과대학

Abstract

An experiment was performed in order to investigate the effects of daily oral administration of propylthiouracil per kg body weight on the metabolic rate and the thyroidal activity in ten, Korean native goats by using the Benedict-Roth Metabolism apparatus and the radioactive iodine-131 in the average environmental temperature at $5.7^{circ}C$. The results obtained were as follows: 1) The mean metabolic rates of the treated group and the control group were $34.5Kcal./m^2/hr.$ and $33.8Kcal./m^2/hr.$ 2) The peak of thyroidal uptake $I^{131}$ rate in the treated group was 20.12% in 48 hrs., following administration of $I^{131}$ and it was 22.62% in the control group in 96 hrs., Highly significant difference was observed(P<0.01).