Korean Journal of Veterinary Research 1972;12(1):37-50.
Studies of Aleolar-Mixed Venous CO2 and O2 Gradients in the Rebreathing Dog Lung
Chang Jun Yu
College of Agriculture, Kyungpook University
반복호흡(反覆呼吸)을 하는 견폐(犬肺)에서의 폐포(肺胞)와 혼합정맥혈액(混合靜脈血液)의 CO2 및 O2 경사도(傾斜度)에 대한 연구(硏究)
유창준
경북대학교 농과대학
Abstract
Another comparison of alveolar gas pressures, in a continuously rebreathing dog lung, with pulmonary arterial (mixed venous) blood, again showed alveolar pressures to be the higher for $CO_2$ and usually $O_2$ (positive ${Delta}Pco_2$, and ${Delta}Po_2$). ${Delta}Pco_2$ was almost invariably positive, it was independant of time and of plasma pH changes produced by acid or bicarbonate infusion, but proportional to blood $CO_2$ level. It was seemingly little affected by the distribution or magnitude of blood flow nor did it result from failure of $CO_2$ equilibrium within the blood, but it did rise with carbonic anhydrase inhibition. ${Delta}Po_2$ was more variable and sometimes negative, particularly at low blood flow rates. It seemed in dependant of time, and plasma pH changes, apart from an inverse relationship with that resulting from $CO_2$ changes. It existed despite considerable potential for gas exchange, and was unaffected by inhibition of the $CO_2$ reactions.
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