Effect of Aconitine upon Autonomic Nervous System in Isolated Rabbit Intestine |
Chang Eop Lee1, Young So Rhee1, Soon Tong Chung2 |
1Department of Veterinary Medicine, College of Agriculture, Seoul National University 2Department of Physiology, Kyung Hee University |
Aconitine이 가토(家兎)의 장관지배신경(腸管支配神經)에 미치는 영향(影響) |
이창업1, 이영소1, 정순동2 |
1서울대학교 농과대학 수의학과 2경희대학교 수의대학 생리학교실 |
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Abstract |
In order to investigate the effect of aconitine upon the parasympathetic innervation, the isolated rabbit duodenal preparation pretreated with atropine and tetrodotoxin were observed. The results obtained in this work were summerized as follows: 1. The excitatory response was evoked by the administration of aconitine ($100{mu}g/ml$). 2. The contraction was blocked by the pretreatment with atropine ($10{mu}g/ml$). 3. The contraction was completely blocked by the pretreatment with tetrodotoxin($10{mu}g/ml$). These experimental evidences indicate that the excitatory response by aconitine is due to the parasympathetic nerves. |
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