Influence of Overdosed Combelen on Korean Native Goats

Nam, Tchi Chou; Sung, Jai Ki; Cheong, Chang Kook

Korean Journal of Veterinary Research 1979;19(1):69-73.

Tchi Chou Nam, Jai Ki Sung, Chang Kook Cheong

College of Veterinary Medicine, Seoul National University

Combelen 과량투여(過量投與)가 산양(山羊)에 미치는 영향

남치주, 성재기, 정창국

서울대학교 수의과대학

Abstract

In order to detect the influence of overdosed combelen on the Korean native goats, 5mg of combelen per kg of body weight were injected intramusculary. Clinical findings, electrocardiograms and some blood chemical values were determined and the results obtained were as follows: 1. After administration of 5 mg/kg dose of combelen the animals were moderately depressed and often tried to take sitting position but showed moderate response to pinching stimulation of skin. 2. Body temperature and respiratory rate were not suppressed but heart rate were accelerated during sedative stage. 3. During sedation a slight change in the QRS complex and T wave appeared but it was not significant. 4. Hemoglobin concentration showed a tendency to decrease. SGOT activities were markedly increased 24 hours after administration of combelen and BUN values were slightly lowered. Blood sugar values were markedly elevated during sedative stage.