| Nickel Toxicity and Its Interaction with Zinc, Copper and Lead in Growing Chicks |
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Jun-hong Park1, Chun-su Kim2 |
1Korea Advanced Institute of Science and Technology
2College of Agriculture, Dan-kook University |
| 초생추에서의 니켈의 독성과 아연·구리 및 납과의 상호작용 |
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박전홍1, 김춘수2 |
1한국과학기술원
2단국대학교 농과대학 |
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| Abstract |
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Nickel toxicity and interactions of nickel with zinc, copper, and lead were studied in glowing chicks fed supplemented diet. Feed intake and growth rate of the chick were reduced by 250mg nickel as a sulfate salt per kg of feed. The toxicity of nickel was decreased by zinc or copper supplementation, but not lead. High nickel feed increased nickel level in kidney and decreased zinc levels in tibia and plasma. However, low zinc levels in tibia and in plasma were reversed by zinc supplementation. Hemoglobin, packed cell volume, and aortic elastin content were increased in chicks fed nickel. These results suggest that nickel toxicity is induced by interference with zinc metabolism. |
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