The morphological changes of exocrine pancreas by pancreatic duct ligation in chicken |
Sae-kwang Ku1, Jae-hyun Lee1, Hyeung-sik Lee2 |
1College of Veterinary Medicine, Kyungpook National University 2Department of Biology, Kyungsan University |
췌관을 결찰한 닭 췌장 외분비부의 형태학적 변화 |
구세광1, 이재현1, 이형식2 |
1경북대학교 수의과대학 2경산대학교 생물학과 |
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Abstract |
To investigate morphological changes in the exocrine pancreas of chicken after pancreatic duct ligation, experimental animals were subdivided to control, 12 hours, 1 day, 2 days, 4 days, 7 days and 10 days groupes and all of three pancreatic ducts of chicken were ligated by surgical procedure and then the morphological changes were observed. In pancreatic ducts, once for a while the ducts were dilated on 12 hours after pancreatic duct ligation and then they were obstructed because of proliferated epithelial cells and connective tissues in pancreatic duct. Marginal dissociation of acini was detected in 12 hours after pancreatic duct ligation and then dissociation of acini was increased with time and finally in 4 days after pancreatic duct ligation the acini showed completely dissociation except periductular regions and around pancreatic islets. Most of dissociated acini cells showed marginal condensation of nuclear chromatin and atropy of cytoplasm, namely, apoptotic features were detected in dissociated acinar cells. Interacinar spaces of dissociated acinar regions were dilated and fulfilled with increased connective tissue and in 4 days after pancreatic duct ligation, deposition of lymphocytes and hemocytes was occurred. |
Key Words:
exocrine pancreas, pancreatic duct ligation, chicken, apoptosis |
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