Minocycline as a treatment of dog with calcinosis cutis

Jang, Hye-Jin; Kang, Min-Hee; Sur, Jung-Hyang; Park, Hee-Myung

doi:2013.53.4.253

Korean J Vet Res > Volume 53(4); 2013 > Article

Brief Communication

Korean Journal of Veterinary Research 2013;53(4):253-256.
DOI: https://doi.org/10.14405/kjvr.2013.53.4.253 Published online December 24, 2013.

Minocycline as a treatment of dog with calcinosis cutis

Hye-Jin Jang¹, Min-Hee Kang¹, Jung-Hyang Sur², Hee-Myung Park¹

¹Department of Veterinary Internal Medicine, of Veterinary Medicine, Konkuk University
²Department of Veterinary Pathology, College of Veterinary Medicine, Konkuk University

Abstract

An 8-year-old, castrated male, Schnauzer dog was presented for evaluation of gradually worsening erythematous papules. Physical examination revealed multiple erythematous papules having a firm, gritty texture located in bilateral ears, dorsal midline, perianal and inguinal area. Skin biopsy revealed aberrant structure, characterized by atrophic epidermal-dermal layer structure with granular materials which was presumed as calcinosis cutis secondary to iatrognic hyperadrenocotricism. By initiating minocycline for 14 days, there was reduction in size, number of calcium deposit with remarkably decreased erythema. This case report presents the clinical trial of minocycline as a potential agent in treating dogs with calcinosis cutis.

Key Words: calcinosis cutis, dog, iatrogenic hyperadrenocorticism, minocycline