Combination therapy of cyclosporine and prednisolone in a dog with systemic lupus erythematosus |
Yeon-Hee Kim, Min-Hee Kang, Hee-Myung Park |
Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University |
|
Abstract |
An 11-year-old, spayed female poodle presented with fever and shifting lameness. Physical examination revealed hyperthermia ($40.6^{circ}C$), and proteinuria was detected upon urinalysis. Increased neutrophils (83%) and decreased viscosity were revealed upon synovial fluid analysis. Serum antinuclear antibody was positive at 1 : 80. Based on these findings, the dog was diagnosed with systemic lupus erythematosus. Immunosuppressive therapy was initiated with prednisolone and cyclosporine, and the condition was markedly improved after the treatments. This case report describes the clinical and laboratory findings, imaging characteristics and successful outcomes after prednisolone plus cyclosporine therapy in a canine systemic lupus erythematosus case. |
Key Words:
antinuclear antibody, cyclosporine, glomerulonephritis, polyarthritis, systemic lupus erythematosus |
|