Korean Journal of Veterinary Research 2000;40(3):563-573.
Evaluation of the recent live vaccination effects against Newcastle disease under field conditions
Chang-seon Song1, Youn-jeong Lee1, Myung-guk Han1, Hwan-woo Seong1, Kyung-soo Kang2, Joong-bok Lee3, Jae-hak Kim1
1Avain Disease Division, National Veterinary Research & Quarantine Service
2Dongducheon Bayer Clinic
3College of Veterinary Medicine, KonKuk University
최근 야외농장에서 실시하고 있는 뉴캣슬병 생독백신 접종효능에 대한 평가
송창선1, 이윤정1, 한명국1, 성환우1, 강경수2, 이중복3, 김재학1
1국립수의과학검역원 조류질병과
3건국대학교 수의학부
Periodic outbreaks of Newcastle disease (ND) caused by velogenic viscerotropic ND virus (vvNDV) has become a major concern in Korea nowadays. Throughout last epidemic, the winter season in 2000, most chicken flocks infected early, under 2-4 weeks of age, showed high mortality up to 50-100%. Serum samples collected from 201 breeder, 284 layer and 112 broiler chicken flocks were examined to evaluate the efficacy of various vaccination methods and programs routinely used for mass vaccination in the field poultry farms. Despite repeated live vaccination, most poultry flocks vaccinated by drinking water route using nipple water supply system failed to produce solid active immune response to NDV during the growing time. In the present study, we applied the spray vaccination technique using Ulvavac or Desvac sprayer to the experimental poultry flocks and examined the efficacy of live vaccination effects induced by it under field condition. Measurable antibody to NDV as well as early protection against vvNDV challenge were found in poultry flocks vaccinated by spray route. Further, we did not found significant post vaccination reactions caused by spray vaccination if properly administered. These data indicate that the spray vaccination will be safe and reliable mass vaccination method for the prevention of ND.
Key Words: Newcastle disease, live vaccine, vaccination effect, spray, drinking water

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