Korean Journal of Veterinary Research 2005;45(2):151-154.
Antioxidant and antitumor activities of ethanol extracts from the fruiting body of Phellinus gilvus grown in oak and artificial sawdust
Mi-hyun Hwang1, Young-hoan Kim2, Kil-soo Kim1, Tae-wan Kim1, Woo-sik Jo3, Sung-guk Choi3, Jong-choon Kim4, Seung-chun Park1
1College of Veterinary Medicine, Kyungpook National University
2Gyeongbuk Veterinary Service Laboratory
3Gyeongbuk Agricultural Technology Administration
4College of Veterinary Medicine, Chonnam National University
참나무 원목 및 톱밥에서 재배된 마른진흙버섯 자실체의 에탄올 추출물에 대한 항산화 및 항암활성
황미현1, 김영환2, 김길수1, 김태완1, 조우식3, 최성국3, 김종춘4, 박승춘1
1경북대학교 수의과대학
2경북가축위생시험소
3경상북도농업기술원 환경농업연구과
4전남대학교 수의과대학
Abstract
The purpose of this study is to examine the elemental compositions, antioxidant and antitumor activity of water, 20%, 40%, 60%, and 80% ethanol extracts obtained from the fruiting body of Phellinus gilvus. In electron donating ability test, the strong activities more than 70% were observed in $80{mu}g/ml$ of 20%, 40%, 60% and 80% ethanol extracts from the fruiting body of P. gilvus grown in oak and sawdust. The antitumor activity was evaluated by sulforhodamine B (SRB) in terms of cell survival level. The tumor cells (sarcoma 180) were treated with various ethanol extracts (water, 20, 40, 60 and 80%). The results showed that all extracts inhibited proliferation showing a dose-dependent manner against tumor cells.
Key Words: Phellinus gilvus, antioxidant, antitumor
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