| Antioxidant and antitumor activities of ethanol extracts from the fruiting body of Phellinus gilvus grown in oak and artificial sawdust |
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Mi-hyun Hwang1, Young-hoan Kim2, Kil-soo Kim1, Tae-wan Kim1, Woo-sik Jo3, Sung-guk Choi3, Jong-choon Kim4, Seung-chun Park1 |
1College of Veterinary Medicine, Kyungpook National University
2Gyeongbuk Veterinary Service Laboratory
3Gyeongbuk Agricultural Technology Administration
4College of Veterinary Medicine, Chonnam National University |
| 참나무 원목 및 톱밥에서 재배된 마른진흙버섯 자실체의 에탄올 추출물에 대한 항산화 및 항암활성 |
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황미현1, 김영환2, 김길수1, 김태완1, 조우식3, 최성국3, 김종춘4, 박승춘1 |
1경북대학교 수의과대학
2경북가축위생시험소
3경상북도농업기술원 환경농업연구과
4전남대학교 수의과대학 |
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| Abstract |
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The purpose of this study is to examine the elemental compositions, antioxidant and antitumor activity of water, 20%, 40%, 60%, and 80% ethanol extracts obtained from the fruiting body of Phellinus gilvus. In electron donating ability test, the strong activities more than 70% were observed in $80{mu}g/ml$ of 20%, 40%, 60% and 80% ethanol extracts from the fruiting body of P. gilvus grown in oak and sawdust. The antitumor activity was evaluated by sulforhodamine B (SRB) in terms of cell survival level. The tumor cells (sarcoma 180) were treated with various ethanol extracts (water, 20, 40, 60 and 80%). The results showed that all extracts inhibited proliferation showing a dose-dependent manner against tumor cells. |
| Key Words:
Phellinus gilvus, antioxidant, antitumor |
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