Effects of formalin on haematology and blood chemistry in crucian carp (Carassius auratus)

Im, Chang-Won; Park, Se-Chang; Heo, Gang-Joon

Korean Journal of Veterinary Research 2006;46(3):249-254.

Chang-Won Im¹, Se-Chang Park², Gang-Joon Heo¹

¹College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University
²College of Veterinary Medicine, Seoul National University

포르말린 침지에 의한 붕어(Carassius auratus)의 혈액학 및 혈액화학치에 대한 영향

임창원¹, 박세창², 허강준¹

¹충북대학교 수의과대학 및 동물의학연구소
²서울대학교 수의과대학

Abstract

To determine the effects of exposure to formalin on the secondary stress indices, changes in haematology and blood chemistry were monitored in healthy crucian carps (Carassius auratus). Fishes were separately exposed in a concentration range of 125 to 500 ppm formalin for 60 min. After exposure, red blood cell (RBC) count and packed cell volume (PCV) were elevated in the 500 ppm formalin exposed group. However, mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were decreased significantly in the 500 ppm formalin exposed group. Total protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, total bilirubin, inorganic phosphorus (IP) and magnesium were significantly increased at a concentration of 500 ppm. Alkaline phosphatase (ALP) and glucose were increased at a concentration of 500 ppm, but this was not significant. Lactate dehydrogenase (LDH) and calcium were significantly decreased at concentrations of 250 and 500 ppm. AST, ALT, glucose and magnesium were significantly increased in the 250 ppm formalin exposed group. These results suggests that formalin exposure might cause some damage in the liver and kidney of crucian carp.

Key Words: crucian carp (Carassius auratus), formalin, haematology and blood chemistry