| The anti-parasitic efficacy of ivermectin and pyrantel pamoate compound against canine Toxocara canis and Trichuris vulpis |
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Heejeong Youn1, Jeong Chan Ra2, Byung Ki Kim2, Bokyoung Bae1, Yong Suk Lim1, Kyong Hee Kim1, Kyong-Eun Lee1 |
1Department of Veterinary Parasitology, College of Veterinary Medicine, Seoul National University
2RNL-Bio |
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| Abstract |
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Toxocara (T.) canis and Trichuris (T.) vulpis are very important canine parasitic nematodes. T. canis parasitize in small intestine and T. vulpis parasitize in large intestine. In order to control of these nematodes, ivermectin and pyrantel pamoate compound was applied to the dogs infected with these parasites naturally and artificially. This drug was composed of $68.0{mu}g$ of ivermectin and 57.0 mg of pyrantel pamoate for small animal, $136.0{mu}g$ of ivermectin and 114.0 mg of pyrantel pamoate for middle animal, and $272.0{mu}g$ of ivermectin and 227.0 mg of pyrantel pamoate for large animal. Ivermectin in this drug is activity to nematodes and ectoparisites. Pyrantel pamoate in this drug is also activity to nematodes. In this experiment, this drug had a good efficacy against T. canis and T. vulpis in the infected dogs. |
| Key Words:
ivermectin, ivermectin and pyrantel pamoate compound, pyrantel pamoate, Toxocara canis, Trichuris vulpis |
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