Histological Observations of the Parenchymal Organs of the Rats, Rabbits and Dogs Injected with Rompun

Oh, Kyu-shil; Lee, Cha-soo

Korean Journal of Veterinary Research 1984;24(2):127-136.

Kyu-shil Oh, Cha-soo Lee

Department of Veterinary Medicine, College of Agriculture, Gyeongbug National University

Rompun을 투여(投與)한 흰쥐 가토(家兎) 및 견(犬)의 실질장기(實質臟器)에 대한 조직학적관찰(組織學的觀察)

오규실, 이차수

경북대학교 농과대학 수의학과

Abstract

The present study was carried out to observe the histological changes of the parenchymal organs of the rats, rabbits and dogs intramuscularly injected with Rompun. The results observed are snmmarized as follows; The hematologic changes of the rabbits and dogs administered with Rompun were a pronounced decrease in erythrocytes and leucocytes. The percentage of lympocytes was decreased, while that of neutrophils was increased. There were severe hyperemia of spleen, hyperemia and extention of the central vein of the liver, centrilobular degeneration of liver, hyperemia and hemorrhage of the kidney, necrosis and hydropic degeneration of renal tubule, hyperemia of pulmonary alveolar septa and pulmonary edema. and in the cases injected with Rompun and histamine or pentothal sodium at the same time, the microscopical findings described above were more conspicuous than the cases injected with Rompun alone.