| Pathological findings on encephalomyocarditis virus infections of swine in Korea |
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Nam-yong Park, Chang-yeong Ri, Chi-young Chung, Hye-young Kee, Seong-yeol Bae |
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College of Veterinary Medicine Chonnam National University |
| 국내에서 발생한 돼지 뇌심근염 바이러스 감염증의 병리학적 관찰 |
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박남용, 이창영, 정치영, 기혜영, 배성열 |
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전남대학교 수의과대학 |
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| Abstract |
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Pathological studies by light and electron microscope were carried out on the twenty piglets naturally affected by encephalomyocarditis virus infection. Gross findings included pale or yellow, small necrotic foci on myocardium, together with pulmonary edema and liver congestion in some cases. On light microscopy, nonsuppurative interstitial endocarcitis, epicarditis and myocarditis, myocardial infarction, and dystrophic calcification or fibtosis were observed in heart. Perivascular cuffings, gliosis and nonsuppurative meningitis were appeared in brain. Focal or diffuse necrosis with mononuclear cell infiltration in lacrimal gland and multifocal necrosis in liver were observed in some cases. Congestion and edema of lung, hyperemia, hemorrhage and deletion of lymphocytes of lymph nodes and spleen were recognized. On electron microscopy, severe swelling and vacuolization of mitochondria and sarcoplasmic reticulum, large intracellular vacuolation and edema, separation and fragmentation of myofibrils were observed. Virus particles were seen in the sarcoplasm of degenerated cardiac muscle cell. |
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