Korean Journal of Veterinary Research 1994;34(2):369-374.
Acute and subacute toxicity of folpet to fingerings of common carp, Cyprinus carpio and goldfish, Carassius auratus
Gang-joon Heo1, Yong-soon Lee2, Yoon-kyu Lim3
1Department of Veterinary Medicine, Chungbuk National University
2College of Veterinary Medicine, Seoul National University
3Department of Veterinary Medicine, Cheju National University
잉어치어(稚魚)와 금붕어에 대한 folpet의 급성(急性) 및 아급성독성(亞急性毒性)에 관한 연구
허강준1, 이영순2, 임윤규3
1충북대학교 수의과대학 수의학과 어류질병학연구실
2서울대학교 수의과대학
3제주대학교 농과대학 수의학과
Abstract
The acute and subacute toxicity of fungicide folpet was evaluated in fingerings of common carp, Cyprinus carpio and goldfish, Carrassius auratus. Dipping of fishes for acute toxicity was performed for a period of 24h, and the TLm value(median tolerance limit) was 1.52 ppm in common carp and 1.45 ppm in goldfish. Severe damages were observed in various organs and among them, clubbing of gill lamella, lytic degeneration and vacuolation of liver cells, and epithelial edema of renal tubules were relatively prominent. The most significant changes were hyperbasophilic foci of liver cells in subacute toxicity test and these can imply the possibility of hepatocarcinogenecity of folpet.
Key Words: folpet, toxicity, hyperbasophilic foci, common carp, goldfish


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